Wound Healing and Pressure ulcers

Pressure ulcers, or pressure sores, are areas of damaged skin or tissue caused by extended pressure that interrupts blood flow to a certain part of the body. Without sufficient bloodflow the affected tissue dies. People at risk are those who are paralysed, use wheelchairs or are not able to change position.

They can develop quickly and often do not heal easily.

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The primary causes that can lead to the appearance of pressure ulcers are:

Extended pressure. When the skin and the subcutaneous tissue are caught between the bone and the surface of a chair or bed for example, blood circulation to that area is more difficult and the tissue is starved of an adequate supply of oxygen and other nutritional substances. This causes irreversible damage or necrosis in the more severe cases.

Frequently changing position is the only way to prevent pressure ulcers. However the friction caused when rolling over in bed for example can damage the skin, making you more vulnerable to this type of lesion.

Shear lesions occur when the skin moves in the opposite direction to the bone. Movement in bed or on a wheelchair, or lying in bed with the head inclined at more than 30° is the most probable cause of shear lesions, which pull the cell walls and capillaries apart, lacerating them.
Pressure ulcers are most likely to occur in patients who are immobilised because of an acute illness, injury or after anaesthesia, even for a short period of time, for example after surgery or an accident. They also occur in the case of chronic spinal cord injuries.

Why Zentrum

ZentrumVit is the first specific product for the body for combating pressure sores and ulcers, providing 100% of the daily requirement of Vitamins A, C, D, E, zinc and selenium. Used with a correct and healthy diet, ZentrumVit provides the ideal conditions for the healing of wounds.

L-arginine stimulates the immune function and increases the production of collagen as a precursor of proline and hydroxyproline. Vitamin C intervenes in the hydroxylation of proline and lysine, stimulating the formation of collagen and the growth of fibroblasts. Vitamin A accelerates healing and reduces susceptibility to infection. Zinc stimulates cellular mitosis and proliferation of fibroblasts.

Before treatment it is recommended to consult a specialist in order to define the best timescale and methods.


The use of arginine is contraindicated for persons who frequently experience outbreaks of herpes virus. The L-arginine amino acid can reactivate episodes of that strain of virus.